Amino Acid Synergy
120 caps Price: $29.00
Amino Acid Synergy is useful as a general supplement to diets that are insufficient in quality protein, for athletes that require additional amino acids to maintain or achieve greater lean body mass, for patients who are cachexic from chronic illness or GI malabsorption, for individuals who are in catabolic states due to stress or illness, for those recovering from surgery or tissue trauma, for people wanting better quality hair and nails and for patients who have been found to have confirmed amino acid deficiencies on metabolic testing.
Amino acids play central roles both as building blocks of proteins and as intermediates in metabolism. Amino acids are called"amino acids" because they all contain an amino group (NH2) and a carboxyl group (COOH), which is acidic. Your body is about
20-percent protein by weight. The 20 amino acids that are found within proteins convey a vast array of chemical versatility.
precise amino acid content, and the sequence of those amino acids, of a specific protein, determines the biological activity of the
protein. Proteins not only catalyze all (or most) of the reactions in living cells, they control virtually all cellular processes.
Humans can produce 10 of the 20 amino acids. The others must be supplied in food. Failure to obtain enough of even 1 of the 10
essential amino acids, those that we cannot make, results in degradation of the body's proteins, including muscle.
Unlike fat and
starch, the human body does not store excess amino acids for later use so amino acids must be consumed every day.
The 10 amino acids that we can produce are alanine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine,
proline, serine and tyrosine. Tyrosine is produced from phenylalanine, so if the diet is deficient in phenylalanine, tyrosine will be
required as well.
The Essential Amino Acids
The essential amino acids are arginine, histidine, isoleucine, leucine,
lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These 10 amino acids are required in the diet.
Alpha-ketoglutarate: Alpha-ketoglutarate is the keto acid produced by deamination of glutamate. It is a key intermediate in the
Krebs cycle, coming after isocitrate and before succinyl CoA. Anaplerotic reactions, or upplementation, can replenish this cycle increasing energy and stamina.
is one of the most important nitrogen transporters in metabolic pathways. The amino groups of amino acids are attached to it by transamination and
carried to the liver where the urea cycle takes place.
Alpha-ketoglutarate is transaminated, along with glutamine, to form the excitatory neurotransmitter glutamate. Glutamate can then be decarboxylated, via glutamic acid
decarboxylase, requiring vitamin B6 (in the form of pyridoxyl-5-phosphate, known as P5P) into the inhibitory neurotransmitter GABA. Adequate P5P was included in this
formula to facilitate such conversions efficiently.
Arginine: Arginine is a complex amino acid that is often found at the active (or catalytic) site in proteins and enzymes due to its amine-containing side chain. Arginine
plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, release of hormones and the production of nitric
Histidine: Histidine is the direct precursor of histamine and is needed to help grow and repair body tissues and to maintain the myelin sheaths that protect nerve cells. It
also helps manufacture red and white blood cells and helps to protect the body from heavy metal toxicity. Histamine also stimulates the secretion of the digestive enzyme,
Isoleucine: Isoleucine belongs to a special group of amino acids called branched-chain amino acids (BCAAs), which are needed to help maintain and repair muscle
tissue. Leucine and valine are the other two branched-chain amino acids. Isoleucine is needed for hemoglobin formation and also helps to maintain regular energy
levels. Isoleucine is also important for stabilizing and regulating blood sugar and energy levels.
Leucine: Leucine is also a member of the branched-chain amino acid family along with valine and isoleucine. The branched-chain amino acids (BCAAs) are found in
proteins of all life forms. Leucine ties glycine for the position of second most common amino acid found in proteins. Leucine is necessary for the optimal growth of infants
and for proper nitrogen balance in adults.
Lysine: Lysine is an essential amino acid which is a major building block for all protein and is needed for proper growth and bone development in children. Lysine helps
the body absorb and conserve calcium and it plays an important role in the formation of collagen. The lysine in this formula may help prevent some common viral outbreaks,
such as cold sores caused by herpes viruses.
Methionine: Methionine is an important amino acid that helps to initiate translation of messenger RNA by being the first amino acid incorporated into the N-terminal
position of all proteins. Methionine supplies sulfur and other compounds required by the body for normal metabolism, detoxification and growth. Methionine reacts with
adenosine triphosphate to form S-adenosyl methionine. S-adenosyl methionine is the principal methyl donor in the body and contributes to the synthesis of many
important substances, including epinephrine and choline.
Phenylalanine: Phenylalanine is an essential amino acid that plays a key role in the biosynthesis of other amino acids and various neurotransmitters.
Threonine: Threonine is an alcohol-containing essential amino acid that is an important component in the formation of protein, collagen, elastin and tooth enamel.
It is also important for production of neurotransmitters and health of the nervous system.
Valine: Valine is a branched-chain amino acid (BCAA) that is closely related to leucine and isoleucine both in structure and function. Valine is a constituent of fibrous
protein in the body and has been found useful in muscle health, and the improvement of mental and emotional disorders, insomnia and nervousness. Valine may also
help treat malnutrition associated with drug addiction.
* Tryptophan was not included in Amino Acid Synergy in order to give the health care practitioner the ability to use this supplement regardless of the patient's
serotonin-related status and to allow the practitioner to add tryptophan (or 5-HTP Synergy or 5-HTP Supreme) on a case-by-case basis.
Who should take Amino Acid Synergy?
Amino Acid Synergy is useful as a general supplement to diets that are insufficient in quality protein, for athletes that require
additional amino acids to maintain or achieve greater lean body mass, for patients who are cachexic from chronic illness or GI malabsorption, for individuals who are
in catabolic states due to stress or illness, for those recovering from surgery or tissue trauma, for people wanting better quality hair and nails and for patients who have
been found to have confirmed amino acid deficiencies on metabolic testing.
How should Amino Acid Synergy be taken?
2 capsules, twice daily (4 capsules) will deliver 3 grams of free-form essential amino acids and is the suggested dose for
More aggressive dosing can be used in cases where the significant addition of muscle mass is desired and also in confirmed amino acid deficiency
Deficiency of free-form amino acids can be suggested on the Designs for Health Metabolic Profiles when organic acids related to energy metabolism (i.e. Krebs
cycle intermediates) are low (please contact BRAVA NUTRITION for more information). Specific amino acid testing is also available via blood-spot and serum testing from
Metametrix Clinical Laboratory (800-221-4640 or metametrix.com
Serving Size 4 capsules
Servings Per Container 30
Amount Per Serving
*Daily Value not established.
Other Ingredients: Microcrystalline cellulose,
magnesium stearate, stearic acid, rice flour.