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>>Brava's "Bredesen Protocol" Pg. 1 Introtroducion

>> Brava's "Bredesen Protocol" Pg. 2 Terminology


Brava's "Bredesen Protocol" Pg. 3 The Science


Brava's "Bredesen Protocol" Pg. 4 Bredesen Cognoscopy


Brava's "Bredesen Protocol" Pg. 5 Nutrition & Herbs Support Cognitive Protection


Brava "Bredesen Protocol" Pg. 6 Protect Your Brain Life Style

Brava "Bredesen Protocol" Pg. 7 Cognitive Self-Testing

Brava "Bredesen Protocol" Pg 8 Summary


Return to >>alzheimersintro.html

The Bredesen Protocol brings together the best of modern Western and traditional Eastern approaches to medical treatment – including nutritional supplements, dietary, lifestyle modifications, and meditation.

The Cognoscopy procedures include the combination of blood tests, DNA genetic tests for the APOE4 gene, simple and free online cognitive assessments, and a Brain MRI with an automatic computer assessment of brain volumes all of which provide critical information to your medical provider of what synapse-destroying processes leading to neuron death and synapse loss that causes the loss of memory and cognitive decline.

Like the standard CBC blood testing at your annual physical that evaluates your cholesterol level, etc., the Cognoscopy consists of Western Medicine** blood tests that determine where you stand in terms of your vulnerability to the three insults of brain inflammation, suboptimal hormones and brain nutrients that the brain requires.

Your brain requires energy and raw materials to power the one billion neurons and one quadrillion energy-demanding synapses for optimal neuronal health, synaptic growth and health maintenance, particularly as one ages!

Refer to Bredesen, 2017, "The End of Alzheimer's" Pgs. 167-169 for a Summary of the Key Tests and Optional Tests for the Bredesen ReCODE Protocol.

After the "Cognoscopy" an individual program can be derived, as Dr. Bredesen states: []

The ReCODE Report™ [Reversing Cognitive Decline]

"The ReCODE Report™ is generated from a very specific set of lab and genome tests curated by Dr. Bredesen. After the results are submitted, a personalized ReCODE Report™ is generated, providing a snapshot of the participant’s current state of cognitive decline."

"The goal is not simply to normalize metabolic parameters, but rather to optimize them. This personalized list highlights the participant’s primary areas of concern and suggests how to specifically address each issue."

The Prevention Program

"The Prevention Program is designed for anyone with dementia in the family, or anyone at risk for Alzheimer’s disease. Utilizing Dr. Bredesen’s proprietary protocol, a personalized preventative program is generated to normalize all metabolic parameters to prevent the onset of cognitive decline. Please do not wait—get your numbers checked and stay sharp for decades."

The Reversal Program

"We have designed an optimal program to stop the progression of cognitive decline and begin improvement—the only effective program to date. This is a comprehensive personalized program that utilizes the Bredesen Protocol to optimize many different metabolic parameters to enhance cognition and reverse cognitive decline."

With a "Cognoscopy" the types of Alzheimer's and what treatments of the Bredesen Protocol one needs can be identifed to prevent or reverse cognitive decline. See the Types of Alzheimer's identified by Dr. Bredesen:

1.Type 1 - inflammatory ("hot") Alzheimer's:
 Patients present predominantly inflammatory symptoms. They have high-sensitivity C-reactive protein, interleukin 6 and tumor necrosis factor alpha, reflecting a chronic inflammatory state. When the NF-ĸB part of inflammation is activated, it also alters gene transcription. Two of the genes turned "on" are beta-secretase and gamma-secretase, the latter of which cleaves APP, thereby promoting synaptoclastic processes.

2.Type 1.5, glycotoxic (sugar-toxic, "sweet") - a mixed subtype: This is an in-between subtype that involves both inflammation and atrophy processes, due to insuline resistance and glucose-induced inflammation.

3.Type 2, atrophic or "cold" Alzheimer's: This is classified as patients presenting an atrophic response. While a completely different mechanism from inflammation, it produces the same end result — it pushes APP in the direction of creating amyloid plaques and Alzheimer's cell signaling.

When you withdraw nerve growth factor, brain-derived neurotrophic factor (BDNF), estradiol, testosterone or Vitamin D — any compound that provides atrophic support — your brain responds by blocking synaptogenesis. As a result, your ability to retain and learn new things is reduced.   

4.Type 3, toxic ("vile") Alzheimer's: These are patients with toxic exposures. Many will have chronic inflammatory response syndrome (CIRS) markers, even though most do not fit the official criteria for CIRS. "They act like CIRS patients (in their labs, not necessarily symptoms) with dementia," Bredesen explains.

They will typically have high transforming growth factor beta and complement component 4A; low melanocyte-stimulating hormone; high matrix metallopeptidase-9; human leukocyte antigen-antigen D related qs (associated with bio toxin sensitivity), yet they rarely have the pulmonary complaints, rashes, fibromyalgia and chronic fatigue typically associated with CIRS. "When you treat those, then they get better. Without treating them, they continue to decline


About Dr. Dale E. Bredesen, MD Visit:

>>Brava's "Bredesen Protocol" Pg. 1

>> Brava's "Bredesen Protocol" Pg. 2>>

>>Brava's "Bredesen Protocol" Pg. 3>>

>>Brava's "Bredesen Protocol" Pg. 4>>

>>Brava's "Bredesen Protocol" Pg. 5>>

Return to >>alzheimersintro.html


*Dale E. Bredesen, MD. "The End of Alzheimer's." The first program to prevent and reverse cognitive decline. Copyright © 2017 Random House, LLC, New York, NY ISBN 9780735216204

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*Nutrigenomics is a branch of nutritional genomics and is the study of the effects of foods  and food constituents on gene expression. This means that nutrigenomics is research focusing on identifying and understanding molecular-level interaction between nutrients and other dietary bioactives with the genome. Nutrigenomics has also been described by the influence of genetic variation on nutrition by correlating gene expression or SNF's  with a nutrient's absorption, metabolism, elimination or biological effects. By doing so, nutrigenomics aims to develop rational means to optimise nutrition with respect to the subject's genotype.

By determining the mechanism of the effects of nutrients or the effects of a nutritional regime, nutrigenomics tries to define the causality|relationship between these specific nutrients and specific nutrient regimes (diets) on human health. Nutrigenomics has been associated with the idea of personalized nutrition based on genotype. While there is hope that nutrigenomics will ultimately enable such personalised dietary advice, it is a science still in its infancy and its contribution to public health over the next decade is thought to be major. While nutrigenomics is aimed at developing an understanding of how the whole body responds to a food via systems biology, research into the effect of a single gene/single food compound relationships is known as nutrigenetics.


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